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Yongkui Jing Selected Research

promyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein

9/2005Benzodithiophenes induce differentiation and apoptosis in human leukemia cells.
9/2005Benzodithiophenes potentiate differentiation of acute promyelocytic leukemia cells by lowering the threshold for ligand-mediated corepressor/coactivator exchange with retinoic acid receptor alpha and enhancing changes in all-trans-retinoic acid-regulated gene expression.
4/2004The PML-RARalpha fusion protein and targeted therapy for acute promyelocytic leukemia.
6/2003The cleavage product deltaPML-RARalpha contributes to all-trans retinoic acid-mediated differentiation in acute promyelocytic leukemia cells.
8/2002Targeted removal of PML-RARalpha protein is required prior to inhibition of histone deacetylase for overcoming all-trans retinoic acid differentiation resistance in acute promyelocytic leukemia.

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Yongkui Jing Research Topics

Disease

24Leukemia
01/2021 - 04/2003
20Neoplasms (Cancer)
10/2020 - 02/2005
12Acute Promyelocytic Leukemia
03/2016 - 08/2002
8Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
04/2022 - 04/2004
8Prostatic Neoplasms (Prostate Cancer)
10/2018 - 05/2004
5Lymphoma (Lymphomas)
12/2012 - 04/2003
3B-Cell Lymphoma (Lymphoma, B Cell)
04/2022 - 06/2011
3Pancreatic Neoplasms (Pancreatic Cancer)
02/2013 - 09/2012
2Breast Neoplasms (Breast Cancer)
12/2017 - 06/2005
2Myeloid Leukemia (Leukemia, Myelocytic)
12/2012 - 03/2005
1Peripheral T-Cell Lymphoma (Lymphoma, T Cell, Peripheral)
03/2019
1Multiple Myeloma
03/2019
1Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous)
03/2019
1Squamous Cell Carcinoma of Head and Neck
01/2019
1Liver Neoplasms (Liver Cancer)
12/2016
1BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia)
06/2011

Drug/Important Bio-Agent (IBA)

9Proteins (Proteins, Gene)FDA Link
03/2019 - 04/2004
9Tretinoin (Retinoic Acid)FDA LinkGeneric
03/2016 - 08/2002
7Arsenic Trioxide (Trisenox)FDA Link
01/2018 - 04/2003
5Histone Deacetylase InhibitorsIBA
03/2019 - 08/2002
5Glutathione Transferase (Glutathione S-Transferase)IBA
12/2012 - 04/2007
5promyelocytic leukemia-retinoic acid receptor alpha fusion oncoproteinIBA
09/2005 - 08/2002
4Biological ProductsIBA
10/2018 - 04/2010
3Histones (Histone)IBA
01/2021 - 02/2016
3PiperazineIBA
02/2020 - 01/2011
3Ethacrynic Acid (Etacrynic Acid)FDA Link
12/2012 - 08/2007
3Caspase 8 (Caspase-8)IBA
11/2012 - 03/2005
3Glutathione S-Transferase piIBA
04/2012 - 05/2004
3Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric
09/2008 - 02/2005
3Aligeron (AS 2)IBA
09/2008 - 04/2003
3Death Domain ReceptorsIBA
02/2008 - 03/2005
3Retinoic Acid Receptor alphaIBA
09/2005 - 06/2005
2methyl 2- cyano- 3,11- dioxo- 18beta- olean- 1,12- dien- 30- oateIBA
10/2020 - 02/2020
2Cytotoxins (Cytolysins)IBA
02/2020 - 02/2016
211-keto-boswellic acidIBA
10/2018 - 01/2017
2Pharmaceutical PreparationsIBA
12/2017 - 12/2016
2AcidsIBA
10/2017 - 08/2007
2Lysine (L-Lysine)FDA Link
12/2016 - 10/2012
2Sulfhydryl Compounds (Thiols)IBA
02/2016 - 02/2005
2ProdrugsIBA
02/2016 - 10/2003
2Prostate-Specific Antigen (Semenogelase)IBA
01/2016 - 08/2015
2artenimol (dihydroartemisinin)IBA
03/2015 - 08/2009
2imidazoleIBA
02/2013 - 09/2012
2ethacrynic acid butyl esterIBA
12/2012 - 08/2007
2Caspase 3 (Caspase-3)IBA
12/2012 - 03/2005
2Ursolic AcidIBA
10/2012 - 09/2012
2Glycyrrhetinic Acid (Po 12)IBA
06/2010 - 01/2010
2EstersIBA
01/2010 - 08/2009
218alpha-glycyrrhetinic acidIBA
01/2010 - 08/2007
2Glutathione (Reduced Glutathione)IBA
01/2010 - 02/2005
2TriterpenesIBA
02/2008 - 05/2006
2boswellic acidIBA
02/2008 - 03/2005
2RetinoidsIBA
09/2005 - 10/2003
2Butyric Acid (Butanoic Acid)IBA
10/2003 - 08/2002
1Checkpoint Kinase 1IBA
04/2022
1Cytarabine (Cytosar-U)FDA LinkGeneric
04/2022
1venetoclaxIBA
04/2022
1PyrimidinesIBA
01/2021
11-phenyl-3,3-dimethyltriazene (PDT)IBA
01/2019
1Cyclin D1IBA
10/2018
1Sorafenib (BAY 43-9006)FDA Link
01/2018
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2018
1Doxorubicin (Adriamycin)FDA LinkGeneric
12/2017
1PropionatesIBA
10/2017
1Amino AcidsFDA Link
12/2016
1Liposomes (Liposome)IBA
12/2016
1Docetaxel (Taxotere)FDA Link
12/2016
1StearatesIBA
12/2016
1Amino Acid Transport Systems (Amino Acid Transporter)IBA
12/2016
1Polyethylene Glycols (Polyethylene Glycol)FDA LinkGeneric
12/2016
1DisulfidesIBA
02/2016
1Androgen Antagonists (Antiandrogens)IBA
01/2016
1ThiohydantoinsIBA
01/2016
1Androgen Receptors (Androgen Receptor)IBA
08/2015
1enzalutamideIBA
08/2015
1IronIBA
03/2015
1Apoptosis Regulatory ProteinsIBA
03/2015
12- (2- methylfuran- 3- carboxamido)- 3- phenylpropanoic acidIBA
06/2013
1Retinoic Acid 4-Hydroxylase (CYP26B1)IBA
06/2013
1oleananeIBA
02/2013
1Oleanolic AcidIBA
02/2013
1CarbamatesIBA
02/2013
1Therapeutic UsesIBA
12/2012
1Cytochromes c (Cytochrome c)IBA
12/2012
1Surface Antigens (Surface Antigen)IBA
11/2012
1LipidsIBA
11/2012
1SolutionsIBA
10/2012
1tocophersolanIBA
10/2012
1MicellesIBA
10/2012
1Tocopherols (Tocopherol)IBA
10/2012
1Member 1 Subfamily B ATP Binding Cassette TransporterIBA
10/2012
1Succinic Acid (Succinate)IBA
10/2012
1polyethylene glycol 2000IBA
10/2012
1compound 20IBA
09/2012
1EnzymesIBA
04/2012
1X-Linked Inhibitor of Apoptosis ProteinIBA
06/2011

Therapy/Procedure

5Therapeutics
04/2022 - 04/2004
3Drug Therapy (Chemotherapy)
01/2019 - 04/2003
1Photochemotherapy (Photodynamic Therapy)
01/2019
1Ligation
11/2012